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KMID : 0361520090200020090
Korean Journal of Psychopharmacology
2009 Volume.20 No. 2 p.90 ~ p.97
Effects of Paroxetine on Symptoms of Hwa-Byung
Min Sung-Kil

Hong Hyun-Ju
Jon Duk-In
Suh Shin-Young
Park Sang-Jin
Song Ki-Jun
Abstract
Objective: This study consists of a single open clinical trial to evaluate the treatment effects of paroxetine on symptoms of hwa-byung, a Korean culture-related anger syndrome.

Methods: Eighty-nine patients with depressive disorders, anxiety disorders, somatoform disorders, or self-labeled hwa-byung were treated with paroxetine (Paxil CR) 12.5-37.5 mg/day for 8 weeks. Treatment effects were evaluated using the Hamilton Depression Scale (HAMD), the State and Trait Anger Inventory (STAXI), and the Hwa-byung Scale.

Results: Scores on all items ; total score on the Hwa-byung Scale ; scores on state anger, trait anger, and anger-in ; total score on the STAXI ; and total score on the HAM-D decreased significantly after eight weeks of paroxetine treatment compared to baseline.

Conclusion: Paroxetine was shown to be effective for treating symptoms of hwa-byung, a chronic anger syndrome.
KEYWORD
Hwa-byung¡¤Anger, Depression, Paroxetine, Hwa-byung scale, HAM-D, STAXI
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